Coluracetam can become the dominant new nootropic in the market for brain supplements in the coming years.
It was invented in Japan and was only first registered in the 2005 Mitsubishi Tanabe Pharmaceutical Corporation. The patent has since been transferred to another company called BrainCells Inc. and they were mostly responsible for carrying out the tests.
During 2010, Phase 2A studies were completed and the company indicated that Coluracetam is suitable for both the treatment of major depressive disorder (MDD) and general anxiety problems.
Coluracetam has many characteristics in common with other Racetams, but there are also some important differences. It is believed that work on increasing the absorption of choline into neurons, even if they are already impaired or damaged. Some evidence suggests that Coluracetam can be particularly effective in areas of the brain involved in visual processing.In the future, We can see Coluracetam, has been taken by more doctors as a drug for the prevention and treatment of retinal and optic nerve injuries.
It has a marked effect on improving eyesight, making colors and shapes more vivid.
Coluracetam is not very common at the moment, but there are thousands of Americans who experimented with these nootropics and saw positive results themselves.
Advantages of Coluracetam:
One of the most interesting benefits of Coluracetam is the possibility of long-term improvement in patients with memory impairment. Since there is only a limited amount of human testing at the moment, animal experiments are the best proof of the possible benefits.
The 2A phases have also shown that this supplement can be effective in treating people who suffer from MDD along with a common anxiety disorder. These positive effects were shown in patients who did not experience any positive effect of using other antidepressants in the past.
Mechanism of action:
The main mode of action for Coluracetam is how an enhancer absorbs choline. This means that it actually increases the level and effectiveness of using choline within the body and brain.
This process using choline is the key to synthesizing a powerful neurotransmitter in the brain, called acetylcholine. This chemical is considered to play a crucial role in memory formation, learning ability, and a number of additional cognitive processes.
Another way of action is potentiation of the AMPA receptors in the brain glutamate.
Of all your neurotransmitters, glutamate is perhaps the most central for synaptic plasticity, which is the ability of your neurons to make new connections to represent new memories.
Due to the novelty of this supplement, there is still no medically recommended dosage for Coluracetam. However, most studies show that a dosage of about 200 mg per day would be beneficial for the average person.
Side Effects & Toxicity:
Again, because of the limited history research on Coluracetam there is not much available information on the toxicity levels of this supplement. However, it would seem that this is relatively safe, given methods of action and similar structures in other Racetam additives.
BrainCells indicated that they did not observe any negative side effects when subjects used Coluracetam doses up to 80 mg 3 times a day.